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progenitor stem cells npscs  (Jackson Laboratory)

 
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    Jackson Laboratory progenitor stem cells npscs
    Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage <t>progenitor</t> stem cells <t>(NPSCs).</t> Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).
    Progenitor Stem Cells Npscs, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/progenitor+stem+cells+npscs/pmc12455596-65-7-11?v=Jackson+Laboratory
    Average 86 stars, based on 1 article reviews
    progenitor stem cells npscs - by Bioz Stars, 2026-07
    86/100 stars

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    1) Product Images from "RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability"

    Article Title: RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability

    Journal: Nucleic Acids Research

    doi: 10.1093/nar/gkaf920

    Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage progenitor stem cells (NPSCs). Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).
    Figure Legend Snippet: Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage progenitor stem cells (NPSCs). Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).

    Techniques Used: Derivative Assay, Comparison, Expressing, Control, Quantitation Assay, Cell Differentiation



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    progenitor stem cells npscs  (Jackson Laboratory)
    86
    Jackson Laboratory progenitor stem cells npscs
    Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage <t>progenitor</t> stem cells <t>(NPSCs).</t> Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).
    Progenitor Stem Cells Npscs, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/progenitor+stem+cells+npscs/pmc12455596-65-7-11?v=Jackson+Laboratory
    Average 86 stars, based on 1 article reviews
    progenitor stem cells npscs - by Bioz Stars, 2026-07
    86/100 stars
    		  Buy from Supplier

    Image Search Results


    Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage progenitor stem cells (NPSCs). Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).

    Journal: Nucleic Acids Research

    Article Title: RNA/DNA-binding protein TDP43 regulates DNA mismatch repair genes with implications for genome stability

    doi: 10.1093/nar/gkaf920

    Figure Lengend Snippet: Differential expressions of MMR genes in iPSC-derived neuronal cells and their regulation by TDP43. ( A ) WB images and histogram illustrate a quantitative comparison of MMR expression in control and siTDP43-treated human iPSC-derived neural lineage progenitor stem cells (NPSCs). Quantitation of protein levels normalized to that of GAPDH. ( B ) Schematic of iPSC, NPSC, and terminally differentiated motor neurons (iMN) utilized in this study. ( C ) IF images revealing the expression of TDP43; and MLH1, MSH2, MSH3, MSH6, and PMS2, and nuclear DNA (DAPI) after siTDP43-mediated KD of TDP43 in iPSC-derived iMNs. ( D ) WB images show the expression of select MMR factors across the following states of cellular differentiation: iPSC, NPSC, and iMN. Error bars indicate mean ± SEM from three independent experiments. Significance values (P-values) are as follows P > 0.5 (ns), P <0.5 (*), P <0.001 (***) and P <0.0001 (****).

    Article Snippet: Terminally differentiated neurons were derived from neural progenitor stem cells (NPSCs) (Jackson Lab) WT (JIPSC1000), TDP43-Q331K (JIPSC1066), TDP43-A315T, and TDP43-M337V, according to established methods [ ].

    Techniques: Derivative Assay, Comparison, Expressing, Control, Quantitation Assay, Cell Differentiation